Matt Ryan will take on a Seahawks pass defense that has allowed just four opposing quarterbacks to throw multiple touchdowns on them through 17 games. Last week Robert Griffin III got off to a red-hot start against Seattle but was limited after his first two drives and ultimately left the game with a major knee injury. Only five quarterbacks have thrown for over 250 yards on the Seahawks this year. Ryan has over 250 yards passing in 12 games this season and two or more touchdowns in 10 outings.